WebMay 1, 2024 · Siglec15 is a type I transmembrane protein containing only one V-set immunoglobulin (Ig) domain and one C2 set immunoglobulin, highly similar to PD-L1 [11], but different from other members of siglec [12], [13]. Siglec15 plays an important role in maintaining immune homeostasis, and its dysregulation may lead to the development of … WebscRNASeqDB a database for gene expression profiling in human single cell by RNA-seq
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WebSIGLEC15 → Sialic acid-binding Ig-like lectin 15 (Siglec-15) Protein also known as : CD33 antigen-like 3 . Gene name : SIGLEC15; Family name : Immunoglobulin >> SIGLEC (sialic acid binding Ig-like lectin) Protein. Recommended ... Websubcell atlas - human The subcellular location page gives an overview of the subcellular location (in three human cell lines) of protein(s) targeted by the antibody/antibodies for … can i donate blood with pots
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WebSialic acid binding Ig like lectin 15 (SIGLEC15) is part of the Siglec family of glycan-recognition proteins. It is expressed in a subset of macrophages. This type-I transmembrane protein possesses two immunoglobulin-like domains, a transmembrane domain and a short cytoplasmic tail. The SIGLEC15 gene is localized on human chromosome 18q12.3. WebSIGLEC15 (CD33L3, HsT1361) protein expression summary. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all … WebNov 23, 2024 · Further study indicates that Siglec15 expression on these leukemia cells suppresses T cell effector and memory population expansion at 7 days post-engraftment (Figure B) and correlates with higher levels of IL-10 and lower levels of CCL17 present in the bone marrow, representing a more immunosuppressive bone marrow milieu. can i donate blood with graves disease