Tīmeklis2013. gada 16. aug. · The RB motif of Edc3 is sufficient for interaction with Rps28a protein. (A) Schematic representation of the operon constructs used to express the RB domain of Edc3 protein (fragment 201–231) fused downstream of a 6His-GST carrier protein and Rps28a protein in E. coli. Numbers above the schematic representation … Tīmeklis2024. gada 31. marts · Taken together, these elements constitute the p53-p21-RB signaling pathway. Following activation of p53, for example by viral infection or induction of DNA damage, p21 expression is upregulated ...
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Tīmeklis2024. gada 19. dec. · Fog2 Rb−/Rb− MEFs and Preadipocytes Have Abnormally Low Levels of Proliferation, and FOG-2 Regulates the Expression of E2F-Regulated Genes (A) Comparison of the timescale of WT and Fog2 Rb−/Rb− E14.5 MEF proliferation before and after the onset of differentiation (J0) by two-way ANOVA with Bonferronni … TīmeklisThe LXCXE Retinoblastoma Protein-Binding Motif of FOG-2 Regulates Adipogenesis Graphical Abstract Highlights dFOG-2 Rbexpression slows down G1/S cycle transition and reduces cell proliferation dTheLXCXEpRb-bindingsiteofFOG-2(FOG-2 Rb)isinvolved in adipogenesis dFog2 Rb /Rbmice are resistant to obesity and present abnormal … overcoming sexual shame
The LXCXE Retinoblastoma Protein-Binding Motif of FOG-2 ... - Cell
Tīmeklis1996. gada 1. sept. · The retinoblastoma protein (Rb) is a tumor suppressor that regulates progression from the G1 phase to the S phase of the cell cycle. Previously, we found that Rb is a transcriptional repressor that is selectively targeted to promoters through an interaction with the E2F family of cell cycle transcription factors--when Rb … TīmeklisAbstract. Oncoproteins from DNA tumor viruses such as adenovirus E1a, simian virus 40 T antigen, and human papillomavirus E7 contain an LXCXE sequence, which they … TīmeklisGo back to where it all began with Ray‐Ban Optics RB5279 eyeglasses. These acetate frames have been worn by cultural influencers, artists, and musicians since the '60s. … overcoming shame and guilt