Citrate transporter family protein

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August undefined, 2024

Websolute carrier family 20 (mitochondrial citrate transporter), member 3; solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1; ... Iacobazzi V, Lauria G, … WebCitrate plays a pivotal role not only in the generation of metabolic energy but also in the synthesis of fatty acids, isoprenoids, and cholesterol in mammalian cells. Plasma levels …

Citrate transport and metabolism in mammalian cells: prostate ...

WebThe partially compromised nodule functioning induces two striking phenotypes: anthocyanin accumulation already displayed 4 weeks after inoculation and shoot biomass deficiency, which is detected by long-term phenotyping. LjNPF8.6 achieves nitrate uptake in Xenopus laevis oocytes at both 0.5 and 30 mm external concentrations, and a possible role ... WebProtein family/group databases. TCDB. 2.A.29.7.1 the mitochondrial carrier (mc) family; Names & Taxonomy. Protein names ... Citrate carrier 1 publication (CIC 1 publication) … inclusion\\u0027s oa

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WebThis gene encodes a member of the mitochondrial carrier subfamily of solute carrier proteins. Members of this family include nuclear-encoded transporters that translocate … WebApr 7, 2024 · The TaALMT1 gene has been found to belong to a new transporter family and regulates the selective efflux of malate. ... and sorghum [48], and its homologue were then identified as OsFRDL4 (a MATE family citrate transporter) in rice [49 ... (OsSTAR1/2, encodes an ABC transporter protein that forms a complex to regulate the efflux of UDP … WebLiver cells import citrate through the sodium-dependent citrate transporter NaCT (encoded by SLC13A5) and, as a consequence, this protein is a potential target for anti-obesity … incarnate word university football conference

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The Mitochondrial Citrate Carrier SLC25A1/CIC and the ... - PubMed

WebMay 14, 2024 · The citrate transport activity of the protein was studied in CT reconstituted liposomes. Our results showed high efficiency of CT for [ 14 C] citrate/citrate exchange with K m 0.01 mM at 25°C. WebMay 14, 2024 · To study the citrate transport mechanism of CT, the citrate transporter gene was expressed in Escherichia coli, and its product was purified. The citrate … inclusion\\u0027s ogWebOct 10, 2013 · The SLC13 family in humans and other mammals consists of sodium-coupled transporters for anionic substrates: three transporters for dicarboxylates/citrate and two transporters for sulfate. This review will focus on the di- and tricarboxylate transporters: NaDC1 (SLC13A2), NaDC3 (SLC13A3), and NaCT (SLC13A5). The substrates of these … inclusion\\u0027s oe

"WebApr 13, 2024 · The inhibited key enzymes in the citrate cycle highlighted inactive energy ... WU75_10380, WU75_10390, and WU75_10385), encoding a choline ABC transporter ATP-binding protein, a choline ABC transporter substrate-binding protein ... transporter periplasmic adaptor subunit and a multidrug transporter. The RND family efflux pumps ... " - Citrate transporter family protein

Citrate transporter family protein

WebDec 15, 2024 · Iacobazzi et al. (1997) determined that the open reading frame of the human citrate transporter gene encodes a mature protein of 298 amino acids and a … WebMar 21, 2024 · This gene encodes a protein belonging to the solute carrier family 13 group of proteins. This family member is a sodium-dependent citrate cotransporter that may …

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WebDec 9, 2024 · The citrate transporter protein (CTP) plays an important role in citrate efflux from the mitochondrial matrix to cytosol that has great importance in oleaginous fungi. ... Most mitochondrial carrier family proteins (MCF) are small, with a length of around 300 amino acids and a molecular weight ranging from 30 to 35 kDa . The hydrophobic ... WebMar 11, 2016 · Multidrug and toxic compound extrusion (MATE) family is the most recent categorized multidrug efflux transporter family, which is a secondary transporter family that couples the translocation of substrates with an electrochemical gradient of cations (such as H + or Na + ions) across the membrane [1, 2].The X-ray structure of the MATE …

WebAn insertion in the rice citrate efflux transporter gene OsFRDL4 increased its promoter activity and improved its expression, thereby enhancing Al tolerance ... The PHT family protein PHT5 in the vacuolar membrane regulates cytoplasmic Pi homeostasis to enhance plant growth under Pi deficiency (Lin et al. 2024; ...

WebSep 29, 2012 · The 2-oxoglutarate carrier (OGC) belongs to the mitochondrial carrier protein family whose members are responsible for the exchange of metabolites, cofactors and nucleotides between the cytoplasm and mitochondrial matrix. Initially, OGC was characterized by determining substrate specificity, kinetic parameters of transport, … WebThe citrate carrier (CiC), a nuclear-encoded protein located in the mitochondrial inner membrane, is a member of the mitochondrial carrier family. CiC plays an important role …

WebSLC13A5. Solute carrier family 13 (sodium-dependent citrate transporter), member 5 also known as the Na+/citrate cotransporter or mIndy is a protein that in humans is encoded by the SLC13A5 gene. [5] It is the mammalian homolog of the fly Indy gene .

WebCitrate transporter family protein Imported. Gene names. Ordered locus names. PFL_2499 Imported. Organism names. Organism. Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) Imported. Taxonomic … incarnate word university football newsWebet al., 2004). Functional gene variants of transport proteins are involved in human diseases, and about 10% of established T2D loci are related to membrane transporters. II. Solute Carrier Membrane Transport Proteins Solute carrier (SLC) proteins are a group of trans-membrane transporters that mediate solute influx inclusion\\u0027s ohWebNov 14, 2008 · Recently, three studies have reported that some MATE proteins are involved in the transport of citrate, which is required for iron (Fe) translocation or … inclusion\\u0027s oiWebFeb 17, 2024 · Liver cells import citrate through the sodium-dependent citrate transporter NaCT (encoded by SLC13A5) and, as a consequence, this protein is a potential target for anti-obesity drugs. incarnate word university graduate programsWebThis gene encodes a sodium-driven citrate transport protein named NaCT. Disease-causing mutations abolish the uptake of citrate in neurons of the brain. ... (NaDC) from the SLC13 family. A number of mutations have been identified in the NaCT transporter gene (SLC13A5) in patients with epileptic encephalography. The Pajor Lab explores what … incarnate word university graduationWebJun 14, 2024 · Introduction. L-lactate is an important metabolite in health and disease 1. Its stereoselective transport across plasma membranes is mainly catalyzed by monocarboxylate transporters (MCTs) of the ... inclusion\\u0027s okWebJan 22, 2024 · The mitochondrial citrate/isocitrate carrier, CIC, has been shown to play an important role in a growing list of human diseases. CIC belongs to a large family of nuclear-encoded mitochondrial transporters that serve the fundamental function of allowing the transit of ions and metabolites through the impermeable mitochondrial membrane. inclusion\\u0027s om