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Cilastatin molecular weight

WebFeb 28, 2024 · Cilastatin was administered subcutaneously to rats (GD 6 to 17) and intravenously to rabbits (GD 6 to 18) at doses up to 1000 and 300 mg/kg/day, … WebCilastatin(MK0791) is a renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Quality confirmed by NMR & HPLC. See customer reviews, validations & product …

Cilastatin sodium Sigma-Aldrich

WebAug 3, 2024 · It is an off-white, nonhygroscopic crystalline compound with a molecular weight of 317.37. It is sparingly soluble in water and slightly soluble in methanol. Its empirical formula is C 12 H 17 N 3 O 4 S•H 2 O, ... Cilastatin sodium was given intravenously to rabbits at doses up to 300 mg/kg/day and to rats subcutaneously at … WebSep 4, 2024 · Cilastatin 81129-83-1 TWA 5 mg/m3 (OEB 1) Internal Imipenem 74431-23-5 TWA 1000 ug/m3 (OEB 1) Internal Further information: RSEN ... Molecular weight : No data available Particle size : No data available SECTION 10. STABILITY AND REACTIVITY covenant university ota admission list https://labottegadeldiavolo.com

Cilastatin CAS#82009-34-5 Dehydropeptidase-I & leukotriene

WebFeb 1, 2024 · It is an off-white, nonhygroscopic crystalline compound with a molecular weight of 317.37. It is sparingly soluble in water and slightly soluble in methanol. Its … WebMolecular Formula C13H20ClNO3 Molecular Weight 273.76 Catalogue Number AR-C02770 Parent Drug CILASTATIN CAS Number 877674-77-6 Cilastatin Ammonium Salt Synonym ammonium (Z)-7-(((R)-2-amino-2-carboxyethyl)thio)-2-((S)-2,2-dimethylcyclopropanecarboxamido)hept-2-enoate Molecular Formula C16H25N2O5S . … Web2 days ago · Journal of Molecular Structure. Available online 12 ... (0.05 M, pH 4.5) at a dose of 100 mg/kg body weight was given to treated rats. A glucometer was used to monitor blood glucose levels one week after the STZ injection. ... Dual drug delivery of vancomycin and imipenem/cilastatin by coaxial nanofibers for treatment of diabetic foot ulcer ... covenant university postgraduate portal

Cilastatin-15N-d3 - Axios Research

Category:Cilastatin C16H26N2O5S - PubChem

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Cilastatin molecular weight

Imipenem: Uses, Interactions, Mechanism of Action

WebJan 10, 2024 · MOLECULAR FORMULA : C16-H26-N2-O5-S MOLECULAR WEIGHT : 358.50 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - … WebThe mean serum half-life of imipenem is about 2 hours, whereas that of cilastatin is 5 to 6.4 hours [488]. The half-life for both drugs is inversely related to birth weight and …

Cilastatin molecular weight

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WebCilastatin Molecular Formula CHNOS Average mass 358.453 Da Monoisotopic mass 358.156250 Da ChemSpider ID 4940183 - Double-bond stereo - 2 of 2 defined stereocentres More details: Featured data source … WebOct 6, 2024 · It is an off-white to yellowish-white, hygroscopic, amorphous compound with a molecular weight of 380.43. It is very soluble in water and in methanol. Its empirical formula is C 16 H 25 N 2 O 5 SNa, and its structural formula is: Imipenem and Cilastatin for Injection, USP (I.V.) is buffered to provide solutions in the pH range of 6.5 to 8.5.

WebCilastatin C16H26N2O5S CID 6435415 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities ... WebShowing 1-6 of 6 results for "cilastatin" within Products. Products Genes Papers Technical Documents Site Content Chromatograms. Filter & Sort. All Photos (1) Cilastatin sodium salt. ... Molecular Weight: 358.45. Compare Product No. Description SDS Pricing; SML1283: 50 mg/mL in DMSO/H 2 O, 1:1: Expand. Hide.

WebCombination of imipenem and cilastatin that is used in the treatment of bacterial infections; cilastatin inhibits renal dehydropeptidase I to prolong the half-life and increase the tissue penetration of imipenem, enhancing its efficacy as an anti-bacterial agent. ... Molecular Formula. C12-H17-N3-O4-S.C16-H26-N2-O5-S. Molecular Weight. 657.8057 ... WebTrade name:Cilastatin (Contd. from page 4) 53.1.21 · Molecular Weight 358.5 g/mol · Odor threshold: Not determined. · pH-value: Not applicable. · Change in condition Melting point/Melting range: Undetermined. Boiling point/Boiling range: Undetermined. · Flash point: Not applicable. · Flammability (solid, gaseous): Product is not flammable.

WebIt is an off-white, nonhygroscopic crystalline compound with a molecular weight of 317.37. It is sparingly soluble in water and slightly soluble in methanol. Its empirical formula is C 12 H 17 N 3 O 4 S•H 2 O, and its structural formula is: Cilastatin sodium is the sodium salt of a derivatized heptenoic acid. briar patch school ohioWebwhite, nonhygroscopic crystalline compound with a molecular weight of 317.37. It is sparingly soluble in water and slightly soluble in methanol. Its empirical formula is … briar patch school columbus ohioWebJan 12, 2024 · Additionally, body weight loss due to cisplatin was not affected by cilastatin (supplementary Fig. 1C). Figure 1 Administration of cilastatin suppressed cisplatin-induced kidney injury. briarpatch school