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WebThe SH2 domain is the most versatile interaction cassette, as its association with a receptor is dependent on phosphorylation of a tyrosine residue in a specific context.45 From: Williams Textbook of Endocrinology (Thirteenth Edition), 2016 Add to Mendeley About this page Enrichment and Interrogation of Cancer Stem Cells A. Jarrar, ... WebOct 23, 2024 · The Spaghetti Nebula - Simeis 147 or SH2- 240. This emission nebula straddles the region between Auriga and Taurus. SH2-240 is believed to be about 3000 light years distant. Due to its large size and being extremely faint, this target is challenging to photograph. I captured the image using my Rokinon 135mm lens and ASI1600 mm Pro … WebJun 22, 2024 · SH2 domain-containing tyrosine phosphatase 2 (SHP2), encoded by PTPN11, plays a fundamental role in the modulation of several signaling pathways.Germline and somatic mutations in PTPN11 are associated with different rare diseases and hematologic malignancies, and recent studies have individuated SHP2 as a central node … chinese number 4